Welcome! This blog contains research & information on lifestyle, nutrition and health for those with MS, as well as continuing information on the understanding of the endothelium and heart-brain connection. This blog is informative only--all medical decisions should be discussed with your own physicians.

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Almost all of MS research is initiated and funded by pharmaceutical companies. This maintains the EAE mouse model and the auto-immune paradigm of MS, and continues the 20 billion dollar a year MS treatment industry. But as we learn more about slowed blood flow, gray matter atrophy, and environmental links to MS progression and disability--all things the current drugs do not address--we're discovering more about how to help those with MS.

To learn how this journey began, read my first post from August, 2009. Be well! Joan

Monday, January 11, 2010

New research for 2010- linking "wedge-shaped" lesions to venous drainage

January 11, 2010 at 9:23am

Researchers in Australia and China note lesions that suggest impairment of venous drainage and link it to CCSVI-

Wedge-shaped medullary lesions in multiple sclerosis.
Qiu W, Raven S, Wu JS, Carroll WM, Mastaglia FL, Kermode AG.

Centre for Neuromuscular and Neurological disorders, University of Western Australia, Australia;
Department of Neurology, Sir Charles Gairdner Hospital, Queen Elizabeth II Medical Centre, Perth, Western Australia, Australia;
Department of Neurology, the Third Affiliated Hospital of Sun yat-sen University, Guangzhou, China.

Multiple sclerosis (MS) is a heterogeneous disease with variable clinical features and magnetic resonance imaging (MRI) findings. We report four MS cases with unusual wedge-shaped lesions in the paramedian ventral medulla oblongata demonstrated on MRI. The clinical features and MRI characteristics of the medullary lesions suggest an impairment of venous drainage.

We propose that the formation of these wedge-shaped lesions may be related to the pattern of venous drainage in the ventral medulla and raised venous pressure due to chronic cerebrospinal venous insufficiency which has recently been described in MS. Copyright © 2010 Elsevier B.V. All rights reserved.

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