Welcome! This blog contains research & information on lifestyle, nutrition and health for those with MS, as well as continuing information on the understanding of the endothelium and heart-brain connection. This blog is informative only--all medical decisions should be discussed with your own physicians.

The posts are searchable---simply type in your topic of interest in the search box at the top left.

Almost all of MS research is initiated and funded by pharmaceutical companies. This maintains the EAE mouse model and the auto-immune paradigm of MS, and continues the 20 billion dollar a year MS treatment industry. But as we learn more about slowed blood flow, gray matter atrophy, and environmental links to MS progression and disability--all things the current drugs do not address--we're discovering more about how to help those with MS.

To learn how this journey began, read my first post from August, 2009. Be well! Joan

Showing posts with label endothelum. Show all posts
Showing posts with label endothelum. Show all posts

Wednesday, October 19, 2011


Shift Work, Cortisol and Environmental Factors in MS

October 19, 2011 at 8:11am

In the news yesterday, a new study showing how shift work (night time work outside of normal daytime hours) doubles a teen's risk of developing Multiple Sclerosis.  

This is considered an "environmental factor" as opposed to a genetic factor.  This new paper comes from the Karolinska Institute in Sweden and was published in the Annals of Neurology.  The researchers did not propose a specific theory as to how shift work might increase the risk of MS, but they did comment on how circadian rhythm disruption might affect melatonin and the immune system.

Here is the complete paper:

Oddly enough, just last week, another published study showed how shift work raises the risk of metabolic disease, higher body mass index (BMI) and cardiac problems in young adults vias cortisol release. This study was undertaken by Dutch researchers and published in the Journal of Clinical Endocrinology-- only a week prior to the Swedish study.  

Here's the abstract for that paper on shift work:

Shift work, or work outside standard daytime hours, has been associated with an increased incidence of metabolic syndrome, and cortisol plays a major role in the development of the disease.