2. We know about Chronic Venous Insufficiency in other parts of the body. This is a recognized condition. Vascular doctors have studied this and treated it with angioplasty for many years. Surprisingly, the jugular and azygos veins had never been studied in depth before. Vascular doctors have studied the veins draining the legs, kidneys, liver and heart, yet not the brain. This is why CCSVI is new; however treating veins is not new. When veins do not work, there is harm to the organ they are supposed to drain.
3. The autoimmune theory for MS is a theory. It has never been proven. Dr. Thomas Rivers created EAE in the 1930s, when he discovered that he could mimic the demyelinating lesions seen in the MS brain. He created these CNS lesions by injecting rhesus monkeys brains with rabbit brain extract. He called this experimental allergic encephalomyelitis--EAE. (now the "a" is for autoimmune.)
We have never- in all of these years of research-- found out exactly why the immune system is activated in MS. Dr. Zamboni's research provides a very plausible reason: slowed venous drainage and reflux causes a break in the blood brain barrier which leads to deposition of foreign particles (including iron) which activates the immune system. He undeerstands this, because this is exactly what happens in venous stasis ulcers formed on the legs in Chronic Venous Disease.
4. People do not like new ideas, especially when they counter the status quo.
5. Doctors do not like patients reading on the internet and telling them what to do.
6. Time is brain...this expression is used for stroke treatment, but is applicable for MS, as well.
7. If MS is re-categorized as a venous disease with neurological complications, many people who make their living treating MS will be affected--researchers, professors, doctors, pharmaceutical reps and CEOS, nurses, and neurologists. Not all of them are happy about this. Many want this to just "go away."
8. Vascular doctors understand the importance of venous return....but not all want to or are able to treat CCSVI.
9. A knowledgeable, informed patient or caregiver is an asset to any doctor. But see #5. We need to read the research and understand the facts.